Oruka Therapeutics - Executive Medical Director, Clinical Development

• Strategic Leadership: • Drives the clinical development strategy for one or more assets • Identifies critical clinical development milestones and ensures team alignment and accountability toward meeting timelines • Provides leadership to the clinical team’s contribution to clinical study reports, key clinical documents, and regulatory submissions • Directly manages and/or mentors Medical Directors, Clinical Scientists and other team members as appropriate • Clinical Trial Design and Oversight: • Leads and contributes to the development of clinical trial protocols, including patient selection criteria, study endpoints, and data collection methods • Oversees the conduct of clinical trials, ensuring adherence to protocols and good clinical practice (GCP) guidelines, working closely with CROs and external partners to ensure efficient execution • Reviews and interprets clinical data to assess the safety and efficacy of the investigational drug, driving timely, data-driven decisions • Manages the clinical contribution to documents required during development (including but not limited to: Clinical Study Protocols, Investigator Brochures, Clinical Study Reports) • Medical Expertise: • Medical Expertise: • Provides deep medical and scientific expertise in the therapeutic area, disease state, and potential drug effects • Reviews clinical data to identify and analyze safety concerns and adverse events, working with the pharmacovigilance team on continual benefit-risk assessment • Stays current with relevant medical literature and clinical trial methodologies • Contributes medical expertise to external interactions, including KOL engagement, advisory boards, and regulatory interactions as appropriate • KOL engagement, advisory boards, and regulatory interactions as appropriate • Cross-Functional Collaboration: • Works closely with other functions including clinical operations, regulatory affairs, medical affairs, biometrics, pharmacovigilance, pre-clinical and project management teams to ensure alignment between clinical strategy and execution in a fast-paced environment • Presents clinical data to internal and external stakeholders as appropriate • People Leadership & Team Development: • Leads and develops a high-impact team • Provides coaching, mentorship, and performance management • Fosters a culture of accountability, collaboration, and scientific rigor • Supports hiring and resource planning in partnership with leadership