Definium Therapeutics - Manager, R&D Finance
Requirements
• Bachelor’s degree in Accounting, Finance, or related field; CPA preferred • Minimum of 5 years of progressive accounting or finance experience; public company experience strongly preferred • Experience supporting R&D and/or clinical trial accounting within the life sciences industry strongly preferred • Demonstrated ability to apply accounting judgment in areas involving estimates, accruals, and complex contracts • Experience with NetSuite or other ERP systems; advanced Excel skills required • Strong analytical, organizational, and problem‑solving skills • Ability to manage multiple priorities and meet deadlines in a fast‑paced environment • Strong communication skills and ability to work effectively with non‑finance stakeholders • The starting base pay range for this position is $111,365.00 - $135,356.00. Compensation will be determined based on several factors including, but not limited to, skill set, years of experience, and the employee’s geographic location. • Employees in this role may be entitled to additional compensation, including bonus and equity. Benefits information is listed on our Jobs Page. The Company provides competitive benefits to employees including: • 100% paid health benefits including Medical, Dental and Vision for you and your dependents • 401(k) program with company match and vesting after the turn of the first month after your start date • Flexible time off • Generous parental leave and some fun fringe perks!
Responsibilities
• Clinical & R&D Accounting • Prepare and review month‑end accruals related to clinical trials, CROs, sites, and other R&D vendors • Maintain recurring journal entries and supporting documentation related to R&D expenses • Prepare quarterly clinical vendor confirmations and audit support schedules • Clinical Trial Financial Oversight • Validate monthly site payments and partner with the Company’s site payment vendor to resolve discrepancies • Review and analyze Clinical Trial Agreements (CTAs), amendments, and site budgets (including Phase 3 trials) for financial accuracy and alignment with forecasts • Track clinical milestones, pass‑through costs, and vendor commitments to ensure accurate expense recognition • Budgeting, Forecasting & Analysis • Perform detailed monthly actual‑versus‑budget variance analysis for R&D and Clinical Operations spend • Maintain rolling forecasts for clinical trial expenses and support updates based on study progress, amendments, and vendor activity • Assist with the annual budget and periodic forecast processes, including scenario analysis related to clinical timelines and spend variability • Cross‑Functional Partnership • Serve as a key finance partner to Clinical Operations and Development teams, translating clinical activity into financial impacts • Coordinate with Legal and Procurement on contract economics, payment terms, and amendments • Collaborate with FP&A to align accounting data with forecasts, cash runway analyses, and management reporting • Controls, Audit & Process Improvement • Assist with the design, execution, and documentation of Sarbanes‑Oxley (SOX) controls related to R&D and clinical accounting • Serve as a primary finance contact for internal and external audit requests related to clinical and R&D spend • Identify and implement process improvements to enhance accuracy, efficiency, and scalability of R&D financial processes • Other • Support special projects, system enhancements, and ad hoc analyses as needed • Perform other general accounting duties as assigned
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