Natera - Senior Software Engineer (Data & AI Solutions)
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Requirements
• Bachelor’s or Master’s degree in computer science or bioinformatics with healthcare or biotech data domain experience preferred • Bachelor’s or Master’s degree in computer science or bioinformatics • 8+ years of experience in data engineering, designing and maintaining data pipelines and cloud data architectures (e.g, Snowflake, AWS, etc) • 8+ years of experience in data engineering, designing and maintaining data pipelines • Strong background in bioinformatics, genomics, or computational biology (required). Understands key genomics and bioinformatics data formats, such as BAM, VCF, FASTQ, common compression techniques for these file formats, and their storage, delivery, and management needs. • Strong background in bioinformatics, genomics, or computational biology (required). • Demonstrated experience supporting scientific R&D, Lab workflows and research teams with production-grade data systems. • Strong proficiency in Python, SQL, and distributed processing frameworks (Spark or equivalent) • Experience with modern orchestration tools (Airflow, dbt, Dagster) • Experience leveraging AI-assisted development tools (e.g., LLM copilots) to accelerate data solution development • Familiarity with building data products that support analytics, ML, or AI applications • Strong data modeling expertise (dimensional, normalized, healthcare-specific schemas) • Experience implementing CI/CD for data pipelines and IaC (Terraform, CloudFormation); Knowledge of data observability, testing, and data quality frameworks • Demonstrated ownership of production-grade data systems and end-to-end pipeline lifecycle • Ability to evaluate emerging data and AI technologies and recommend scalable solutions • Exposure to vector databases, embeddings, semantic search, or RAG-based architectures is a plus • Proven ability to operate effectively in fast-paced environments, balancing speed, rigor, and compliance • Strong written and verbal communication skills with ability to collaborate across engineering, analytics, and business stakeholders • Experience working with healthcare, life sciences, or other highly regulated data, including hands-on HIPAA compliance. • The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations. • $125,000 - $156,300 USD • OUR OPPORTUNITY • OUR OPPORTUNITY • Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. • The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.
Responsibilities
• Design, build, and maintain the data products that support R&D, analytics, Lab and scientific workflows, from initial design through deployment and iterations • Build and maintain data pipelines for large and complex datasets, from raw inputs through derived and analysis-ready datasets. • Design and enforce de-identification and privacy-preserving architectures that meet HIPAA and related regulatory requirements while remaining usable for research. • Design scalable data models to power analytics, reporting, and downstream applications. Maintain high standards of data quality, accuracy, lineage, and observability across data pipelines. • Partner closely with R&D scientists, bioinformatics teams, and software engineers to translate research needs into well-structured, reusable data assets. • Optimize storage, retrieval, and lifecycle management for large scientific files (E.g. sequencing data, intermediate artifacts, derived datasets). • Drive rapid prototyping efforts to support exploratory, proof-of-concepts, and early-stage initiatives, while guiding the transition to production-grade systems. • Implement best practices for data quality, validation, lineage, observability, and reproducibility to enable a trusted 360° view. • Collaborate with product managers and domain experts to translate requirements into technical solutions • Establish golden paths (templates, examples, docs) and contribute to shared data product catalogs, patterns, and best practices used by other engineers • Provide technical guidance and mentorship to mid-level engineers
Benefits
• Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program! • For more information, visit www.natera.com.
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