dayhoff-labs - Computational Scientist, Biocatalysis

• Role-description signals matter more than CV signals here — a PhD, where you trained, prior industry experience, and Nature papers are all non-essential. We care about: • A track record of putting computational designs into wet labs and tracking what happened (the worked-to-didn't ratio matters less than whether you can explain the failures mechanistically) • Fluency across the protein ML stack (at least some of ESM, AlphaFold or Boltz, RFdiffusion, ProteinMPNN / LigandMPNN, docking) and comparable fluency in biocatalysis fundamentals (mechanism, kinetics, common cofactors, expression bottlenecks) • Good taste in tool selection • Comfort talking to chemists and fermentation engineers about your model choices in their language • Highly preferred • Experience driving projects from substrate to characterised design without waiting to be handed the next step • Scepticism about your own outputs — you'll flag a junk prediction rather than over-claim • Compensation is highly competitive. We're also able to sponsor visas for the right candidate.