Natera - Lead Bioinformatics Scientist (Oncology)

• Master’s degree in bioinformatics (or a related field) with 10 years of post-graduate experience, or PhD with 5 years of post-graduate experience (preferred). • Expert knowledge of bioinformatics tools for NGS, including sequencing QC and secondary analysis such as variant calling. • Experience with WES/WGS/targeted sequencing of tissue and cfDNA, and with somatic variant calling (SNVs, indels, CNVs, fusions) on these data. • Working knowledge of statistical methods for assay performance evaluation, and ability to collaborate with biostatisticians on study design. • Strong programming and scripting skills in Python, R, and shell. • Fluency in exploratory data analysis and visualization of complex datasets, with the ability to distill observations into actionable recommendations. • Deep understanding of NGS workflows from sample extraction to sequencing, and the ability to link bioinformatic findings to wet lab root causes. • Ability to communicate effectively with wet lab groups and cross-functional partners, and to explain technical concepts clearly. • Ability to work independently while managing multiple objectives and timelines. • Comfort adapting quickly when experimental results change the plan, and a desire to work in a fast-paced environment with high impact in a small team. • PREFERRED: • Experience supporting regulated or clinical-grade assay development (e.g., CLIA/CAP, FDA submissions), including analytical validation studies. • Familiarity with clinical genomics, including oncogenic drivers, actionable biomarkers, targeted therapies, and variant interpretation in oncology. • Experience with translational or real-world data analysis, including integrating clinical and genomic data. • The pay range is listed and actual compensation packages are based on a wide array of factors unique to each candidate, including but not limited to skill set, years & depth of experience, certifications and specific office location. This may differ in other locations due to cost of labor considerations. • $130,900—$163,600 USD • OUR OPPORTUNITY • OUR OPPORTUNITY • Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives. • The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.