Flagship Pioneering, Inc. - Senior / Principal Data Infrastructure Engineer

• Bachelor's degree in Computer Science, Data Engineering, Computational Biology, Proteomics, or a related technical field; advanced degree is a plus. • 8+ years of hands-on experience in data infrastructure, data engineering, informatics, or related fields, preferably in proteomics, bioinformatics, or other biotech environments. • Proven track record of independently designing, building, and operating terabyte-scale data systems in a biotech or life sciences environment. • Demonstrated ability to set technical direction and deliver complex projects with minimal oversight. • Expertise in cloud infrastructure (e.g., AWS, Azure), Kubernetes, and infrastructure management as code tools (CFN, CDK, Terraform, ARM). • Deep understanding and experience of data modeling with database and data warehouse systems (e.g., Postgres, Redshift, Snowflake). Strong familiarity with lakehouse and medallion-style architectures (e.g., Delta Lake, Iceberg). • Experience with data pipeline architecture and workflow orchestration (e.g., Flyte, Dagster, Airflow), including APIs, schedulers, and software integration. • Strong proficiency in Python, SQL; comfortable with R. • Hands-on experience with DevOps, software design lifecycle (SDLC), and automation tools (e.g., Terraform) and CI/CD practices. • Strong written and verbal communication skills, with the ability to explain technical decisions to both technical and non-technical colleagues. • Preferred: • Experience using LLMs and agentic tooling (e.g., Claude, Model Context Protocol servers) to build interactive, natural-language query interfaces that give scientific teams direct access to data is highly preferred. • Experience with mass spectrometry and/or NGS data sets and biomarker discovery workflows. • Experience with LIMS and data management systems (e.g., Dotmatics, CORE LIMS). • Familiarity with laboratory automation systems, including integration with robotic and sample management platforms. • Flagship Pioneering is a bioplatform innovation company that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the companies Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture.  Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies, and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com. • Flagship Pioneering and our ecosystem companies are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. • committed to equal employment opportunity • At Flagship, we recognize there is no perfect candidate. If you have some of the experience listed above but not all, please apply anyway. Experience comes in many forms, skills are transferable, and passion goes a long way. We are dedicated to building diverse and inclusive teams and look forward to learning more about your unique background. • Recruitment & Staffing Agencies: Flagship Pioneering and its affiliated Flagship Lab companies (collectively, “FSP”) do not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to FSP or its employees is strictly prohibited unless contacted directly by Flagship Pioneering’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of FSP, and FSP will not owe any referral or other fees with respect thereto. • Recruitment & Staffing Agencies • The salary range for this role is $108,000 - $209,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. Expedition Medicines currently offers healthcare coverage, annual incentive program, retirement benefits and a broad range of other benefits. Compensation and benefits information is based on Expedition Medicines's good faith estimate as of the date of publication and may be modified in the future.