Iovance Biotherapeutics - Senior Director, Program Team Lead

• Program Strategy • Program Strategy • Own the program strategy and vision from early development through registration and commercialization, ensuring alignment with Iovance's TIL platform strategy. • Frame program decisions around clinical probability of success, regulatory path, and commercial value. • Develop and present strategic options and trade-off analyses to senior leadership and governance bodies. • Track the competitive landscape in solid tumor oncology and cell therapy; translate insights into program-level actions. • Cross-Functional Execution • Work to align SME deliverables with overall development strategy, anticipating risks, proposing alternative scenarios and working with the cross functional team to drive accountability. • Partner with the Program Manager to align domain area strategy & execution plans with asset level strategy across all functions, including Clinical, Regulatory, Commercial and CMC. • Own program dashboards/reporting that keeps leadership informed on program status, timelines, strategic roadmap progress, upcoming inflection points, and open risks. • Governance and Stakeholder Management • Serve as the primary strategic voice for assigned programs in governance forums and executive reviews. • Proactive escalation & driving of resolution recommendations with senior leadership. • Support due diligence, business development, and investor-related activities for assigned programs. • Must adhere to Iovance Biotherapeutics’ core values, policies, procedures, and business ethics. • Perform miscellaneous duties as assigned. • Required Education, Skills, and Knowledge • Advanced degree (PhD, PharmD, MD, MBA, or equivalent). • 11+ years in clinical drug development with strong CMC experience in oncology, in particular experience with CGT, especially CAR-T, viral, TIL and other products with. • Working knowledge of the global clinical and commercial landscape in oncology and cell therapy. • Strong strategic and analytical skills — able to synthesize inputs from clinical, regulatory, commercial, and CMC functions into clear recommendations. • Track record leading cross-functional teams through multiple development phases, including regulatory submissions and health authority interactions. • Proficiency with program and portfolio management tools and timeline oversight. • Proven ability to influence senior stakeholders and motivate teams without direct authority. • Comfortable operating in a fast-moving biotech environment with shifting priorities. • Preferred Education, Skills, and Knowledge • Background in program management, strategy, or portfolio leadership within a biotech setting. • Experience contributing to commercial launch planning or lifecycle strategy from a development role. • History of engagement with FDA, EMA, or other health authorities in oncology or cell/gene therapy • Physical Demands and Activities Required • The physical demands described here represent those an employee may encounter while performing the essential functions of this job. Reasonable accommodation may be provided to enable individuals to perform these functions. • Ability to remain in a stationary position for extended periods • Ability to move about within an office or remote workspace and exert up to 10 pounds of force occasionally • Visual acuity sufficient for preparing and analyzing data, viewing computer screens, and extensive reading • Repetitive motion involving wrists, hands, and/or fingers • Ability to communicate effectively to exchange information • Ability to engage in analytical, conceptual, and problem‑solving activities in a dynamic business environment • Mental: Clear and conceptual thinking ability; excellent judgment, troubleshooting, problem-solving, analysis, and discretion; ability to handle work-related stress; ability to handle multiple priorities simultaneously with a sense of urgency; and ability to meet deadlines • Mental: • Work Environment • Work Environment • This job operates in a professional or remote office environment and requires operating standard office equipment and keyboards. • The annual base salary we reasonably expect to pay is listed. Individual pay decisions depend on various factors, such as primary work location, complexity and responsibility of the role, job duties/requirements, and relevant education, experience and skills. • Pay Transparency • $270,000—$290,000 USD • The statements contained in this document are intended to describe the general nature and level of work being performed by a colleague assigned to this description. They are not intended to constitute a comprehensive list of functions, duties, or local variances. Management retains the discretion to add or to change the duties of the position at any time. • Iovance is committed to cultivating and offering a diverse and inclusive work environment. As an equal-opportunity employer, our employees and applicants will be considered without regard to an individual’s race, color, religion, sex, pregnancy, national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information, military and veteran status, and any other characteristic protected by applicable law. If you need assistance or accommodation to apply to one of our opportunities, please contact [email protected]. • By voluntarily providing information and clicking “Submit Application”, you explicitly consent to the collection and use of your personal information for the purposes described above and in our Candidate Privacy Notice.