relationrx - Senior Scientist, Model Systems

• Integrate human primary cell lines into robust monoculture and co-culture models that are capable of large batch production and compatible for high throughput readouts, with the necessary quality control (QC). • Characterise and optimise multiplexed imaging and biochemical assays that provide readouts for functional phenotyping. • Transition manually developed perturbation models into an automated arrayed screen. • Contribute to the development and implementation of new technologies, workflows, and operational infrastructure. • Carrying out data analysis and relevant quality assurance protocols. • Communicate outcomes of your work to team members and external parties in written or verbal reports. • Stay up to date of relevant scientific literature and incorporate new findings into research project planning and experiment design. • Proactive identification of potential project issues and communication of proposed solutions to the team. • Communicate closely with cross-functional colleagues across biology, machine learning and automation disciplines and assist with solving complex scientific challenges and accelerate programme delivery. • PhD with 5+ years experience and demonstrable knowledge in assay development and/or target validation. • Strong background in culturing of primary and immortalised cell lines as well as functional disease relevant endpoints with the aim of ensuring required reproducibility and sensitivity in those assays. • Hands-on experience in image capture and data interpretation using High content imaging with cell painting. • Scientific knowledge of fibrosis across various tissues. • Knowledge of CRISPR/Cas9 gene editing for modulating gene expression in 2D and 3D cell systems. • Prior experience running pathway-modifying perturbation screens. • Experience with automated laboratory systems. • Extensive knowledge in industry-standard large ‘omic dataset handling and recording keeping. • Excellent communication, influencing and interpersonal skills, with the ability to thrive in a collaborative, cross-functional, matrixed environment • High motivation, scientific rigor and be able to comfortably operate in a fast-paced, evolving biotech setting • Personally, you • Are comfortable working in a matrixed environment, balancing multiple stakeholders and contributing effectively across teams. • Take ownership of your work, proactively seek opportunities to contribute, and enable others to do their best work. • Communicate openly and directly, give and receive feedback constructively, and handle challenging conversations with respect. • Actively seek out diverse perspectives, build strong working relationships, and contribute to shared goals across teams. • Embrace challenges with openness and resilience, set high standards for yourself, and strive to deliver meaningful outcomes. • Working Style & Culture at Relation • At Relation, we operate in a matrixed, interdisciplinary environment, where impact is driven through collaboration across scientific, technical, and operational domains. We collaborate, and you will partner with colleagues across multiple teams and projects, contributing your expertise while aligning to shared company priorities. We work together and win together! The patient is waiting! • Recruitment Agencies • Please note that Relation does not accept unsolicited resumes from agencies. Resumes should not be forwarded to our job aliases or employees. Relation will not be liable for any fees associated with unsolicited CVs. • Relation is a committed equal opportunities employer.